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doi: 10.1093/rheumatology/kead253 127 WiseLMStohlW
While these effects demonstrate dopamine system modulation relevant to ADHD pathophysiology (the disorder involves dopamine dysregulation), amphetamine-induced stereotypy models psychosis and stimulant abuse, not ADHD symptoms
References 1 Nature Medicine (2014)Nicotinamide N-methyltransferase knockdown protects against diet-induced obesity (preclinical)
BPC-157 at either 0.0045 mg/lb or 0.0000045 mg/lb intraperitoneally produced almost complete reversal of this supersensitivity when co-administered with haloperidol or given therapeutically afterward
Oral delivery is pharmacokinetically disadvantaged versus injection for systemic targets, but may have a genuine local advantage for GI-tract applications because degradation products act locally before absorption
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