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For calcium imaging studies, male Naval Medical Research Institute (NMRI) mice (Taconic Biosciences, BomTac:NMRI) were used (aged 1828 days)

Clinical studies have used schedules more intensive than those seen in recovery practice: patients with Parkinson's disease received 1,400 mg three times a week for four weeks (Hauser et al., Movement Disorders 2009, PMID 19230029), while studies on skin lightening used 1,200 mg twice a week for six weeks (Alzahrani et al., Cureus 2025, PMID 40013212)

Kelly FJ, Blomberg A, Frew A, Holgate ST, Sandstrom T

Best for: combination use alongside oral or IV forms not as a primary treatment

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