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Phase 2: active escalation (weeks 8 to 24) As doses increase toward the therapeutic range of 8 to 12 mg, heart rate effects become more apparent
Over the following 6 to 8 days, the concentration gradually declines as your body metabolizes the compound, primarily through hepatic pathways that do not interact with cytochrome P450 enzymes
Most side effects are mild, but if severe reactions occur, consult your healthcare provider immediately
Such data are summarized in Fig
[Source: Fierce Pharma ] January 2025 The FDA fast-tracked tirzepatide for cardiovascular risk reduction in obesity patients, following landmark trial results showing significant benefit beyond weight loss
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