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Understanding how GLP-1 regulates inflammation will provide insights into the pleiotropic benefits of GLP-1 receptor (GLP-1R) agonism

LDL-cholesterol uptake by HepG2 hepatic cells Ability of anti-PCSK9 antibodies and peptide-antibody fusions to block PCSK9 activity and restore LDL-C uptake was tested in vitro by plating in 96-well plates 2 10 4 HepG2 cells per well in DMEM medium supplemented with 10% lipoprotein deficient serum and cultured overnight