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There is no method to extend this window without compromising peptide integrity
So the practical takeaway is not oral is better or SC is better. It is: pick one route, follow the documented per-dose figure for the vial you have, and keep the route constant so that whatever you observe is not confounded by a mid-stream route change
The injection is providing you with the necessary B vitamins regardless of your food intake, which is helpful especially if you have trouble eating a balanced diet (due to illness or other reasons)
The evidence is preclinical (mouse and cell studies)
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