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These results indicate that many mutations acquired during early rounds of PANCE and dual selection were not essential for gasdermin D cleavage and, in some cases, were detrimental to protease efficiency in the context of GD_L variants
are employed by Gubra
| DOI : 10.3998/panc.2014.7 JA
The primary efficacy analysis employed a last-observation-carried-forward approach within a modified intent-to-treat population, which included all participants who had at least one follow-up visit after randomization
Stopping without lifestyle changes may lead to weight regain
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