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However, under heat stress, the production of misfolded proteins may exceed the capacity of cellular protein quality-control systems
Keywords cytochrome p450 glucuronic acid glutathione prodrug toxic metabolites drug design 1
The crystal structure of meningococcal FetA indicates that this outer membrane protein binds to and perhaps directly internalizes ferric iron, consistent with its broad specificity (Saleem et al., 2012
The inhibition of TECs ferroptosis can effectively ameliorate renal interstitial fibrosis and significantly reduce the expression of profibrotic factors through the inhibition of TGF-/Smad signaling
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