The approval came after clinical trials involving 3,477 patients (2,519 on Zepbound and 958 on a placebo): Patients taking 5mg of Zepbound lost 15% of their body weight (study 1) Patients taking 10mg of Zepbound lost 19.5% (study 1) and 12.8% (study 2) of their body weight Patients taking 15mg of Zepbound lost 20.9% (study 1) and 14.7% (study 2) of their body weight Patients taking the placebo lost 3.1% (study 1) and 3.2% (study 2) of their body weight Zepbound was released to market on December 5, 2023, with six available dosages available to those with a prescription: 2.5mg, 5mg, 7.5mg, 10mg, 12.5mg, and 15mg
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However, surgery and medication remain very different treatment approaches
"Although slowed gastric emptying is integral to reducing post-prandial blood glucose responses marked slowing might also increase the propensity for longer intragastric retention of food." PubMed Abstract Nausea is another common side effect, stemming from prolonged food retention in the stomach and the medications impact on the brain
Our medical team stays vigilant for common reactions such as nausea or gastrointestinal changes, promptly addressing concerns to maintain your comfort and safety