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GLP-1 medications improve glucose control and reduce systemic inflammation, which may reduce glycation stress on collagen

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Administration site: Subcutaneous injection as close to the affected spinal segment as practical

2 Akkermansia muciniphila and obesity consistent microbiome findings A landmark meta-analysis of gut microbiome studies found Akkermansia muciniphila is consistently depleted in individuals with obesity, type 2 diabetes and metabolic syndrome and enriched in lean, metabolically healthy controls