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The unfulfilled needs in the management of GLP-1 RAs among patients with T2D and established or high risk of ASCVD that are considered within this paper include: assessment and categorisation of CV risk among patients with T2D
Assessment should include medication review to identify other constipating agents, digital rectal examination when indicated, and consideration of abdominal imaging if obstruction is suspected
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Tamoxifen can substantially reduce breast cancer incidence in high-risk patients, but many eligible women do not take the drug because of concerns about side effects
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