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FDA approval timeline June 2023 : Phase 2 results in the New England Journal of Medicine 17.5% weight loss at 24 weeks December 2025 : TRIUMPH-4 results 28.7% weight loss March 2026 : TRANSCEND-T2D-1 results glycemic control + weight loss May 2026 : TRIUMPH-1 results up to 28.3% / 70 lbs over 80 weeks Late 2026 (est.) : Remaining TRIUMPH trials complete
This means there is more likely to be some bias in the results
Res Wash DC
Enhancement of activities relative to fatty acid oxidation in the liver of rats depleted of L-carnitine by D-carnitine and a gamma-butyrobetaine hydroxylase inhibitor
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