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3.1.2 Exenatide As the first GLP-1R agonist approved for T2DM, EX is a new class of compound and a synthetic product of exendin-4, which is a compound naturally derived from the Gila monster and has multiple hypoglycemic mechanisms: inhibiting of glucagon release from cells, slowing of gastric emptying, decreasing appetite and increasing glucose-dependent insulin secretion ( Lipotoxicity induced by saturated free fatty acids plays a vital role in renal injury in obese patients ( There is little research on the weight loss effect of EX on simple obesity patients, and more clinical trials are conducted on patients with T2DM

GSH is the central reference antioxidant for studying redox signaling, free-radical chemistry, and cellular oxidative-stress responses

PMID: 6145137 | doi:10.1016/0149-7634(84)90023-2 Graf MV et al

Effect of pre-operative HbA1c and blood glucose level on the surgical site infection after lumbar instrumentation surgery

L-theanine is a relaxing amino acid that is present in the green tea leaves