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In full-thickness wound studies in animal models, topical application of GHK-Cu accelerated wound closure, increased granulation tissue formation, and enhanced angiogenesis compared to vehicle controls
The results are mixed: some musculoskeletal studies show enhanced local healing with proximal injection, while others show comparable efficacy between subcutaneous and peri-lesional routes
Amylin receptor activation requires far less compound than simultaneous triple receptor agonism
This helps allow the skin to heal and recover and reduces the risk of side effects
A handful of human trials have been registered -- some in Croatia, where most of the original research originated -- but published results are sparse and methodologically limited
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