Mulvihill EE, Drucker DJ (2014) Pharmacology, physiology, and mechanisms of action of dipeptidyl peptidase-4 inhibitors
Leptin also reduces the levels of orexin, which is another peptide located in the same region and like MCH, induces hunger [28]
This means that patients who have already been started on Wegovy or Zepbound for weight management in recent months may be eligible to transition to the Bridge without re-starting from scratch but the prescriber must complete a retrospective attestation of the qualifying BMI and clinical condition at the time of initial prescription
Seiwerth S, Milavic M, Vukojevic J, et al
In some cases, treatments such as topical therapies or other clinical options may support recovery, but most individuals see regrowth once weight stabilizes and internal balance returns