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Glipizide is effective only in individuals with functioning pancreatic beta cells and is therefore used exclusively in type 2 diabetes

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The functional outcome of 4E-BP1 is further modulated by stress-responsive kinases that bypass canonical mTOR signaling

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The N-terminal zinc-ribbon domain of C16orf87 is predicted near the catalytic channel of HDAC1 but with only moderate confidence (mean pLDDT ~ 70, inter-chain PAE ~ 20 ) (Fig