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GLP-1 aids in decelerating stomach emptying and promoting insulin release while curbing appetite

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For silencing FOXO4, specific small interfering RNA (siRNA) was employed, with a negative control siRNA, and transfection was conducted using Lipofectamine 3000 [2]

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Moreover, the Pt-induced ROS production further disturbs the normal function of DNA, mitochondria, microtubule, ion channels, and biomolecules, thus, inducing neuroinflammation, demyelination, and neuronal apoptosis in the process of PIPN (Lim et al., 2010