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Similarly, another study found that L-Carnitine treatment for 30 days in the rabbit model of cholesterol-induced atherosclerosis can reduce LDL and increase HDL levels 25

Metabolism: Clin Exp (2019) 92:8297

this is thought to contribute to the substantial weight loss observed in early-phase clinical trials, though the precise human mechanistic contribution remains under investigation

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The approved drugs contain the base form of semaglutide