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Biochem Pharmacol 2000
Moreover, compared to wild-type mice, IRI or nephrotoxic insults led to more severe kidney injury and renal dysfunction in NRF2-deficient mice, as well as higher mortality [207]
Finally, one trial in 239 participants already suffering from chemotherapy-induced peripheral neuropathy reported a reduction in the severity of neuropathic symptoms with ALCAR (3 g/day for eight weeks) compared to placebo (93)
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