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Starting at a low dose of 0.25 mg in the first week is a crucial step to minimize potential gastrointestinal side effects that many patients experience when beginning treatment with semaglutide GLP-1
They help regulate blood sugar by: Increasing insulin secretion when blood glucose is high Reducing glucagon release Slowing gastric emptying Reducing appetite and caloric intake Originally developed for type 2 diabetes, these drugs also promote weight loss, leading to off-label use and new FDA approvals specifically for obesity management
10.1016/j.pmpp.2017.07.006 2 Agudelo-RomeroP.ErbanA.RegoC.Carbonell-BejeranoP.NascimentoT.SousaL.et al
These cases are a small sample, McElroy says, but in both, the tirzepatide seemed to activate the past history of anorexia, McElroy says
