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Identical to carrier proteins, they can reduce the intracellular concentrations of the chemotherapeutic agents in the cancer cells
However, protocols extending beyond 6 months in humans rely on extrapolation rather than controlled studies
Combination therapy also modestly improves weight, blood pressure, and lipid parameters, with reductions in body weight of approximately 11.5 kg versus SGLT2i alone, though evidence for additive effects on weight loss is inconsistent
Should your level come back low, the follow-up question becomes what's causing it
Cohen et al., 2012
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