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doi:10.1016/j.jiph.2021.10.020 6
For researchers dealing with constipation from GLP-1 medications , evening dosing can also be beneficial
And then comes the cruel loop
Some doctors may prescribe it off-label (for a condition it wasn't approved to treat) to help promote weight loss in people with obesity or overweight
In one study of 3,127 adults with obesity but not diabetes, those taking the highest dose lost an average of 27 pounds, or 12.4 % of body weight, over 72 weeks
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