Glycolysis plays a major role for adenosine triphosphate supplementation in mouse sperm flagellar movement
doi: 10.3389/fphar.2023.1176206 Received 28 February 2023 Accepted 29 March 2023 Published 06 April 2023 Volume 14 - 2023 Edited by Yong Gao, Guangzhou University of Chinese Medicine, China Reviewed by Dingguo Zhang, Jinan University, China Qi Tong Fan, Nanchang University Fuzhou Medical College, China Updates Copyright 2023 Tong, Huang, Chen, Tu and Wang
Ensuring Quality and Efficacy of GLP-1 Agonists: Analytical Challenges and Solutions in Therapeutic Peptide Production Glucagon-like peptide-1 (GLP-1) agonists represent an exciting class of drugs that have gained significant attention in recent years for their potential to treat type 2 diabetes mellitus (T2DM) and obesity

Current UK professional guidance emphasises: Patients should inform their surgical team and anaesthetist that they are taking a GLP-1 medication as soon as surgery is planned Healthcare professionals should specifically ask about GLP-1 use during preoperative assessment, as patients may not recognise these medications as relevant to their surgery The decision to continue or pause GLP-1 therapy should be made on an individual risk-based assessment , considering the type of surgery, the specific GLP-1 agent, dose escalation status, presence of gastrointestinal symptoms, and the patient's clinical circumstances Many patients can safely continue GLP-1 medications perioperatively with appropriate precautions, while those at higher risk may benefit from temporary cessation The Summary of Product Characteristics (SmPC) for GLP-1 medications notes the delayed gastric emptying effect, which anaesthetists consider when planning perioperative care

This pilot study aims to identify microbial signatures associated with glycemic responses to GLP-1 RA