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Due to its short half-life, it requires frequent dosing to maintain elevated GH levels
McTernan, Mark Christian BMC Medicine.2023;[Epub] CrossRef Molecular Mechanisms of Obesity-Induced Development of Insulin Resistance and Promotion of Amyloid- Accumulation: Dietary Therapy Using Weak Organic Acids via Improvement of Lowered Interstitial Fluid pH Yoshinori Marunaka Biomolecules.2023
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Increlex (mecasermin) is authorized by the European Medicines Agency for the same pediatric severe primary IGFD indication
Some patients also are hesitant to start a drug they will have to take long-term because they worry about the consequences of being on the medication for years to come
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