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Discussion KOA is one of the most common disabling joint disorders, and approximately 44.7% of patients with OA are at risk of developing a disability in their lifetime [4]

The phase 3 SELECT trial highlighted semaglutide 2.4 mgs capability to cut the risk of major adverse cardiovascular events by 20% in individuals with obesity compared to a placebo, leading to an updated label for Wegovy

If tissue becomes scarred, it is known as fibrosis

I suspect it will be some time before we get a trial with semaglutide or Tirzepatide to really understand whether a direct brain level is needed

Pre-workout:1 scoop (10g) with 300-600ml of water 15-30min before your workout