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These computational findings are consistent with experimental and preliminary clinical evidence, including observational studies and randomized clinical trials, suggesting that metformin may reduce the risk of AD and comorbid AD in individuals with DM2 while also enhancing cognitive performance 52,53,54,55,56,57
Presented for research literature review only Orer GE et al
doi: 10.1111/bph.15485
doi: 10.1007/s00395-015-0465-x 32 XueSWasserfallCHParkerMBruskoTMMcGrailSMcGrailKet al
Integration with testosterone optimization protocols represents another consideration for men
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