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The theory is that overnight fasting reduces stomach acid production, creating a less hostile environment for probiotic organisms to survive the journey to the intestines
In the ATTAIN-1 trial, people on the highest dose lost about 11% of their body weight over 72 weeks, against 2% on placebo
Because of this dual action, it may: Suppress appetite more strongly Improve insulin response Produce greater weight loss for some patients Because both medications affect overlapping systems, taking them together does not usually provide extra benefit
The pulse is too brief to translate into the kind of clinical results patients expect when they think about growth hormone optimization, especially in adults seeking improvements in body composition, sleep depth, and recovery
Updated June 2026 Medically reviewed by Dr
