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GLP-1 receptors are expressed not only in pancreatic beta cells but also in various tissues including the cardiovascular system, kidneys, and immune cells such as macrophages and lymphocytes

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Did the committee strike the right balance between scientific evidence, clinical experience, and patient access

Insulin Resistant Mechanisms Underlying the Action of DPP-4i on Hypertension Insulin resistance (IR) is considered as a pathological condition in which cells fail to respond normally to the hormone insulin (109)