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This hormone plays a key role in blood sugar control, digestion, and appetite regulation

Individuals with pre-existing gastrointestinal issues, elderly patients, or those engaging in intense physical activities may have a higher risk due to increased vulnerability to dehydration and electrolyte imbalances

Medical Options: For those at high risk, doctors might prescribe thiazide diuretics to lower urinary calcium or potassium citrate to alkalinize urine and raise citrate

Details of ongoing phase 3 studies can be found on ClinicalTrials.gov

For instance, the restoration of mitophagy has been shown to suppress HG-induced tubular ferroptosis and renal damage in diabetic mice (200)