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For many people, nausea improves within a few weeks as the body adapts

Published protocol Mouse: 5 mg/kg intraperitoneal, repeated over weeks (Baar et al., 2017)

PlexusDx prescribers recommend starting at the lowest effective dose, then titrating slowly every 1-4 weeks to minimize GI upset while maximizing weight-loss results

These effects are most common during dose escalation and often lessen over weeks, but they can be severe enough to fragment sleep while they last

While effective for many men, these medications may provide limited benefit when low sexual desire or impaired central arousal is a contributing factor