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Ethical principles of the study complied with the European Directive 010/63/E, the Law on Amendments to the Animal Protection Act (Official Gazette 37/13), the Animal Protection Act (Official Gazette 135/06), the ordinance on the protection of animals used for scientific purposes (Official Gazette 55/13), Federation of European Laboratory Animal Science Associations (FELASA) recommendations, and the recommendations of the Ethics Committee of the School of Medicine, University of Zagreb
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Mechanistic studies reveal that 5-Amino-1MQ treatment decreases adipocyte size by over 30% and reduces adipocyte volume by more than 40% compared to untreated obese controls
Wang Q, Jiang J, Chen W, Jiang H, Zhang Z, Sun X
Besides NOX, H 2 O 2 is also generated in peroxisomes, mitochondria, and the endoplasmic reticulum [74, 75]
