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The drugs success contributed to AbbVies decision to raise its full-year adjusted earnings guidance, reflecting confidence in Rinvoqs continued growth trajectory

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5.3 Hypoxia-activated prodrugs Hypoxia-activated prodrugs (HAPs) represent a rational strategy to exploit the hypoxic nature of tumors by selectively delivering cytotoxic agents to oxygen-deprived regions while sparing normoxic healthy tissue (271, 272)

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