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Microsomal stability assays measure metabolism mediated by CYP and FMO enzymes, which are enriched in the microsomal fraction

Glutathione is one of the body's most powerful antioxidants, playing a vital role in detoxification, immune defense, and cellular repair[4]

The work still happens naturally, but with better coordination and resources behind it

Many nutrients have their action INSIDE the cell, which means that testing serum and blood levels just give us an indication of what may be available but that is assuming everything else is working properly: cellular activity, enzyme activity, receptor activity, etc