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While some reports suggest that the medication has the potential to ameliorate fibrosis and reduce liver fat, others have raised concerns about exacerbation of underlying liver disease
Additional studies have shown that LacCer activates cytosolic phospholipase A2 (PLA2) and MAV2 in astrocytes and that, autocrinely, this pathway leads to NFkB activation and transcription of inflammatory factors, contributing to the pathogenesis of EAE and MS
Updated in January 2016
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Anyone currently on blood thinners without medical supervision, given the vascular mechanism
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