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For example, KMO deficiency in male mice elevates KYNA and induces depressive-like behaviours via 7nAChR antagonism, impairing cholinergic modulation of prefrontal circuits, effects that are reversed by restoring 7nAChR signalling [71]

Under high oxidative stress this balance is shifted even further towards GSSG and this has consequences for overall cysteine balance

One of the less talked-about effects of significant or rapid weight loss is the potential loss of lean muscle and bone density