Pernicious anemia, a condition caused by a vitamin B12 deficiency, often goes unnoticed, leaving people feeling sluggish, weak, or even confused
Here are some common causes: Dietary deficiency, mainly in vegans and vegetarians Pernicious anemia, an autoimmune issue with intrinsic factor production Gastric disorders, like atrophic gastritis or gastrectomy Malabsorption conditions, including Crohns disease and celiac disease Certain medications, like proton pump inhibitors and metformin Signs and Symptoms Requiring Medical Intervention Its important to know the signs of vitamin B12 deficiency
They may also be necessary when certain medications interfere with B12 absorption or in any other diagnosed condition specifically impacting B12 uptake
However, development was discontinued in 2007 after the largest Phase IIb trial failed to demonstrate statistically significant weight loss compared to placebo
Because of that, B12 shots give new life to patients (if lucky to have had a correct diagnosis) who would otherwise be living a round-the-clock nightmare