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Extended Data Figure 5 C347 6.36b F stabilizes the interaction interface between GLP-1R and NAMs

Understanding Tirzepatide and Semaglutide: Mechanisms of Action Semaglutide and another medication are both classified as GLP-1 receptor agonists, yet they exhibit notable differences in their mechanisms of action

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Definition and Overview GLP-1 agonists are synthetic compounds designed to activate the GLP-1 receptors in the body, mimicking the actions of the endogenous GLP-1 hormone