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This effect helps prevent post-meal spikes in blood sugar, which are often a challenge for individuals with diabetes
Evolution of GLP-1-Based Therapeutics The therapeutic use of GLP-1RAs has evolved significantly, offering various formulations that provide different efficacy, administration routes, and dosing flexibility [19] [20]
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Finally, expression levels of target genes were determined by the ratio between the levels of target genes and the levels a housekeeping gene ( gapdh )
Results Study Selection and Characteristics A total of 23 phase III randomized controlled trials met the inclusion criteria, contributing 48 treatment arms conducted exclusively in individuals with T2DM (see Table 1 for a summary of trial-level and treatment-arm characteristics, and Supplementary Table S1 for detailed study characteristics)
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