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Another described Dr
Whilst these effects are therapeutically beneficial for glycaemic control and weight reduction, they can potentially lead to reduced overall nutrient intake in some individuals
The SURMOUNT-5 clinical trial published in The New England Journal of Medicine showed that Zepbound (tirzepatide) achieved an average weight loss of 20.2% compared to 13.7% with Wegovy (semaglutide) at 72 weeks
NNMT is a cytosolic enzyme that methylates nicotinamide (vitamin B3) using S-adenosylmethionine (SAM) as a methyl donor
Lancet 2024;403:1027-1050
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