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Sermorelins effects on recovery allow higher training volumes than might otherwise be sustainable, but progressive overload should still follow structured programming rather than simply training as much as possible
Research indicates that weight loss triggers neurohormonal responses designed to defend against further weight reduction, creating a biological drive to eat that may override medication effects in susceptible individuals
Free Radical Biology and Medicine, 62, 1325
Dehydration is a well-established cause of headache and may occur with GLP-1 medications due to reduced fluid intake (from appetite suppression) or increased fluid loss (from gastrointestinal side effects such as nausea, vomiting, or diarrhoea)
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