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Activation of MC1R on melanocytes stimulates melanin production and distribution, resulting in increased skin pigmentation even without UV exposure [2]

medications are a steady drip

Regardless, this data suggests we could combine both in clinical practice when indicated and available, as further studies are guaranteed to demonstrate the efficacy of combination therapy in this setting

Physiological GH secretion occurs in pulses, which can reach about 10ng/ml in men and 14ng/ml in women [11]

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