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Visual observation suggested a pattern where the plaques in saline-treated mice were generally larger and more densely stained compared to the plaques in GHKCu-treated cohorts (Figure 3)
DHAR and GR were also found in the soluble fraction of peroxisomes, whereas membrane bound APX proteins have been shown to be present in P
The pathology culminates in an immune-mediated rearrangement and destruction of the synovium in joints, causing a range of painful mobility-impairing symptoms
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