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Your body is eating less, losing fat, and recalibrating how it perceives temperature
Presented for research literature review only Sorrentino L et al
It is believed to work through several pathways: Blocking voltage-dependent sodium channels , reducing neuronal excitability Enhancing GABA (gamma-aminobutyric acid) activity , an inhibitory neurotransmitter Antagonising glutamate receptors , further dampening excitatory neurotransmission Inhibiting carbonic anhydrase enzymes , though the clinical significance of this effect varies Topiramate is taken orally, typically once or twice daily
Injection of glioblastoma cells (C6) IGF-1R antisense cells into rats carrying an established wild-type C6 tumour caused complete regression of the tumours
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