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This direct delivery bypasses the skin barrier, which can limit the absorption of topically applied ingredients, ensuring more consistent and potent therapeutic levels
Other GLP-1 drugs have been approved as diabetes medication and prescribed off-label for weight management
Zepbound targets two hormone receptors (GLP-1 and GIP), while Wegovy targets one
Expected Weight Loss Results Clinical trials of semaglutide 2.4 mg injections showed meaningful weight reduction
A 2025 study published in Obesity found that GLP1 users lost 7.7% of body weight on semaglutide and 12.4% on tirzepatide after one year, roughly half the weight loss seen in randomized trials
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