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Early-phase human trials are small, well-controlled studies centered on safety, reproductive hormones, and surrogate markers such as ovarian reserve tests and sperm parameters ahead of any efficacy trials

Dosage refers to the total amount of a peptide introduced into a research system during an experiment

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Ipamorelin binds to the GHS-R1a receptor on pituitary somatotrophs, triggering growth hormone release through phospholipase C activation and intracellular calcium mobilization