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Sikiri, P., et al
Lower Risk Across All Key Outcomes with GLP-1RA Compared with DPP-4 inhibitors, GLP-1RA use was associated with significantly lower risks of MACE (hazard ratio [HR]: 0.66), VTE (HR: 0.49), kidney disease progression (HR: 0.77), and all-cause mortality (HR: 0.26)
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Multiple approaches were investigated across academic and industrial laboratories, including enteric coatings to bypass stomach acid, protease inhibitor co-formulations, nanoparticle encapsulation, mucoadhesive delivery systems, and permeation enhancers
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