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People of thiamin deficiency include those affected by: pregnancy chronic illness inadequate dietary intake alcoholism bariatric surgery chronic diuretic therapy Prolonged, untreated thiamin deficiency may lead to Wernicke-Korsakoff syndrome, a disorder that can affect people with chronic alcoholism, gastrointestinal disorders, or AIDS

Because its endogenously produced rather than purely synthetic, researchers frequently compare it with lab-synthesized copper-peptide analogs to assess how closely manufactured versions replicate the naturally occurring molecules structure and behavior

If landmarked correctly however, it is safe to use