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All authors made edits and corrections and reviewed and approved the final version of the test

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Reviewing certifications, affiliations, and patient feedback can help ensure you are working with a qualified professional.

b , The alternation of surface mainly derived from an outstanding conformational change of the loop between Pro124 and Ala133, with which the side chains of Arg152 formed multiple hydrogen bonds in the wild-type, but not His152 in the mutant

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