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It is not, on its own, a decision
The transmembrane rather than paracellular transport of lipophilic compounds was supported by the demonstration of an inverse association between lipid/water partition coefficient and increased transport rate following calcium chelation, i.e., disrupting intercellular junctions increased the transport of hydrophilic but not of lipophilic small organic molecules [31]
Even where compounding becomes permitted, it does not mean these peptides are FDA-approved drugs
Some peptides, particularly BPC-157 and Larazotide, have shown promise for the inflammation and barrier-function pathways that often drive IBS symptoms
FDA status matters The FDA has not approved most research peptides for human therapeutic use
