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In addition to directly providing metabolites, CAFs regulate tumor metabolism through paracrine cytokine signaling

Stomach issues are common with higher doses

These approaches should be viewed as complementary to, not replacements for, medical treatment when indicated, and may not produce significant GLP-1-mediated clinical effects on their own

Patients should inform their doctor if they develop symptoms that could indicate thyroid problems while taking these medications, including a lump or swelling in the neck, hoarseness, difficulty swallowing, or shortness of breath

[1] An analysis of clinical trials found that obese women reduced their calorie intake and lost weight