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Enrichment analysis of the lipidomics data showed the main-class metabolites that differed between CM and CF ( p 1.5) included sphingomyelins, glycerophosphocholines, and sphingolipids (Fig
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We developed a sensitive, high-throughput, scalable system for profiling the cleavage activity of natural and evolved BoNT proteases on thousands of substrates simultaneously by adapting the genetic circuitry of PACE into a pooled activity-enrichment assay
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